Commercial accelerators: Compact superconducting synchrocyclotrons with magnetic field up to 10 T for proton and carbon therapy

Based on a brief review of accelerators widely used for proton-ion therapy and for curing patients over the last 20 years, the necessity and feasibility of creating compact superconducting synchrocyclotrons with a magnetic field value up to 10 T are outlined. The main component of modern commercial facilities for proton-ion therapy is an isochronous cyclotron with room-temperature or superconducting coils which accelerates protons to 250 MeV or a synchrophasotron with carbon-ion energy reaching 400 MeV/nucleon. Usually the ions are delivered from the accelerator to the medical-treatment room via transport lines, while irradiation is produced by means of a system that is comprised of pointing magnets, collimators, and energy degraders mounted on a rotating gantry. To greatly reduce the price of the facility (by an order of magnitude) and to facilitate the work of hospital personnel, the isocentric rotation of a compact superconducting synchrocyclotron around the patient is proposed. Estimates of the physical and technical parameters of the facility are given.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic €32.70 /Month

Buy Now

Price includes VAT (France)

Instant access to the full article PDF.

Rent this article via DeepDyve

Similar content being viewed by others

Modern compact accelerators of cyclotron type for medical applications

Article 03 September 2016

Feasibility Study on the Use of a Superconducting Synchrocyclotron and Electron Beam Ion Source for Heavy-Ion Therapy

Article 24 October 2018

Research and Development of the SC230 Superconducting Cyclotron for Proton Therapy

Article 01 January 2021

References

  1. Yu. N. Denisov, V. P. Dmitrievsky, V. P. Dzhelepov, A. A. Glasov, V. V. Kolga, A. A. Kropin, M. Kuzmyak, L. M. Onischenko, V. S. Rybalko, L. A. Sarkisyan, E. Shvabe, D. P. Vasilevskaya, B. I. Zamolodchikov, and N. L. Zaplatin, “Problems of Theory and Modelling of a Ring-Shaped Phasotron with Spiral Field Distribution,” Nucl. Instrum. Methods 21, 85–88 (1963). ArticleADSGoogle Scholar
  2. G. Dutto, R. Baartman, P. Bricault, I. Bylinsky, A. Hurst, G. MacKenzie, R. Poirier, Y.-N. Rao, L. Root, R. Ruegg, and G. Stinson, TRIUMF High Intensity Cyclotron Development for ISAC. TRIUMF, H. Vancouver, in Proceedings of the International Conference on Cyclotrons and Their Applications, Tokyo, Japan, 2004, pp. 82–86.
  3. Fitze, M. Bopp, A. Mezger, J.-Y. Raguin, P. Schmelzbach, and P. Sigg, “Developments at PSI,” in Proceedings of the International Conference on Cyclotrons and Their Applications, Tokyo, Japan, 2004, pp. 67–71.
  4. F. Cole, P. V. Livdahl, F. E. Mills, and L. C. Teng, “Loma-Linda Accelerator Project,” in Proceedings of the Particle Accelerator Conference PAC-1989, Chicago, United States, 1989, pp. 737–741.
  5. Y. Jongen, W. Kleeven, and S. Zaremba, “New Cyclotron Developments at IBA,” in Proceedings of the International Conference on Cyclotrons and Their Applications, Tokyo, Japan, 2004, pp. 87–91.
  6. A. Geisler, C. Baumgarten, A. Hobl, U. Klein, D. Krischel, M. Schillo, and J. Timmer, “Status Report of the ACCEL 250 MeV Medical Cyclotron,” in Proceedings of the International Conference on Cyclotrons and Their Applications, Tokyo, Japan, 2004, pp. 87–91.
  7. P. Miller, F. Marti, D. Poe, M. Steiner, J. Stetson, A. Stolz, and P. Zavodszky, “Status of the Coupled Cyclotron Facility at NSCL,” in Proceedings of the International Conference on Cyclotrons and Their Applications, Tokyo, Japan, 2004, p. 62.
  8. D. Riffugiato, L. Calabretta, and G. Cuttone, “INFN-LNS, Catania, Ten Years of Operation with the LNS Super Conducting Cyclotrons,” in Proceedings of the International Conference on Cyclotrons and Their Applications, Tokyo, Japan, 2004, pp. 118–120.
  9. H. Eickhoff, “HICAT — The German Hospital-Based Light Ion Cancer Therapy Project,” in Proceedings of the European Particle Accelerator Conference EPAC-2004, Lucerne, Switzerland, 2004, pp. 290–294.
  10. H. Blosser, R. Burleigh, D. Johnson, T. Kuo, F. Marti, J. Vincent, J. Wagner, A. Zeller, E. Blosser, G. Blosser, R. Maughan, and W. Powers, “Medical Accelerator Projects at Michigan State University,” in Proceedings of the Particle Accelerator Conference, United States, 1989, pp. 742–746.
  11. H. Blosser, J. Bailey, R. Burleigh, D. Johnson, E. Kashy, T. Kuo, F. Marti, J. Vincent, A. Zeller, E. Blosser, G. Blosser, R. Maughan, W. Powers, and J. Wagner, “Superconducting Cyclotron for Medical Application,” IEEE Trans. Magn. 25, 1746–1754 (1989). ArticleADSGoogle Scholar
  12. H. Blosser and X. Wu, “Compact Superconducting Synchrocyclotron Systems for Proton Therapy at PSI,” Nucl. Instrum. Methods Phys. Res., Sect. B 40/41, 1326–1330 (1989). ArticleADSGoogle Scholar
  13. V. P. Dmitrievskii, et al., in Proceedings of the 3rd Discussion on Isochronous Cyclotron U120M, ChSSR, 1973.
  14. M. Gordon and X. Wu, “Extraction Studies for a 250 MeV Superconducting Synchrocyclotron,” in Proceedings of the Particle Accelerator Conference, United States, 1987, pp. 1255–1257.
  15. X. Wu, PhD Thesis (Michigan State Univ., United States, 1990).
  16. T. Antaya, US Patent PCT/US2007/001628 (2007).
  17. M. Miller, Mevion Medical Systems. www.StillRiver-Systems.com. Cited 14 May 2010.
  18. E. Pedroni, “Status of Hadron Therapy Facilities Worldwide,” in Proceedings of European Particle Accelerator Conference EPAC-2008, Genoa, Italy, 2008.
  19. Varian Medical Systems. http://www.varian.com
  20. U. Amaldi, S. Braccini, and P. Puggioni “High Frequency Linacs for Hadrontherapy,” Rev. Accel. Sci. Technol. 2, 111–131 (2009). ArticleGoogle Scholar
  21. A. Garonna, “Synchrocyclotron Preliminary Design for a Dual Hadrontherapy Center,” in Proceedings of IPAC’10, Kyoto, Japan, 2010, pp. 552–554.
  22. Y. Jongen, M. Abs, A. Blondin, W. Kleeven, S. Zaremba, D. Vandeplassche, V. Aleksandrov, S. Gursky, O. Karamyshev, G. Karamysheva, N. Kazarinov, S. Kostromin, N. Morozov, E. Samsonov, G. Shirkov, V. Shevtsov, E. Syresin, and A. Tuzikov, “Compact Superconducting Cyclotron C400 for Hadron Therapy,” Nucl. Instrum. Methods Phys. A 624, 47–53 (2010). ArticleADSGoogle Scholar

Author information

Authors and Affiliations

  1. Joint Institute for Nuclear Research, Dubna, Moscow oblast, 141980, Russia A. I. Papash, G. A. Karamysheva & L. M. Onishchenko
  1. A. I. Papash